Is there no risk in Vitamin B group because it is water-soluble? The professor told you that this is not the case

I posted tourette on 2019-2-25, taking vitamin B6? , reader Elliot sent three pieces of information about Vitamin B6 poisoning in the response column on 2025-2-1. Vitamin B6 is a part of the so-called vitamin B group. Since group B is water-soluble,...


I posted tourette on 2019-2-25, taking vitamin B6? , reader Elliot sent three pieces of information about Vitamin B6 poisoning in the response column on 2025-2-1.

Vitamin B6 is a part of the so-called vitamin B group. Since group B is water-soluble, most people, including some doctors, believe that group B is not at risk of poisoning (drugs often appear in TV advertisements in Taiwan that promote group B). But, this is not the case. Please read the following 4 articles about group B poisoning published by me:

Anti-aging drug - The adverse effect of excessive cardiovascular disease risk of Vitamin B3 (yelic acid is Vitamin B9)

The practice of vitamin and nonsense

The higher the concentration of vitamin B12, the higher the mortality rate

The first information sent by readers Elliot is Australia's ABC Warnings high doses of vitamin B6 over a long period could cause irreversible nerve damage published by News on 2025-1-7. Its preface (abstract) is:

Since 2020, TGA (relative to the FDA in the United States) has received 119 reports of peripheral neuropathy caused by vitamin B6 poisoning. Vitamin B6 is usually obtained without prescription, but only those who are diagnosed with lack of vitamin B6 need to take supplements. TGA is currently considering an application that requires the storage of B6 products behind the cabinet. [Note: TGA is a minus written by Therapeutic Goods Administration] The second information sent by Elliot, a reader, was published by ABCNews in Australia on 2025-1-27. Its preface (abstract) is:

Ten people from all over Australia shared with us their experience of vitamin B6 poisoning. Terri-Lynne South, a general practitioner and nutritionist, said the number of cases may be underestimated. The Australian Drug Administration said it is considering a proposal to strengthen supervision, including changing the sales location and sales method of B6 vitamins.

Reader Elliot Special Note: TGA has received 121 confirmed cases of B6 poisoning. Currently, Australia stipulates that supplements/health foods containing more than 10 mg of B6 should be marked as "warning" (similar to boxed warning in the United States). TGA is discussing replenishment/health care foods containing 5 mg to 200 mg B6 as medicine directed by the drug, and consumers are not allowed to buy them by themselves as food or adult medicine. The commercially available multi-preparation group B in Taiwan is mostly 20 mg~50 mg, and the dose of single-preparation B6 is higher. In addition, I believe that overdose poisoning of B6 in Taiwan is also under-reported (being regarded as other neurovenous disease changes). I asked several friends in private, and some of them were caused by the neuropathy caused by B6 overdose. However, they rarely conducted relevant investigations and diagnosis (health insurance payment verification system), not to mention the general rights of internal and medical departments (very regular 200% verified). The third information sent by

reader Elliot is the Megavitamin-B6 syndrome published on Wikipedia. Its first paragraph says: "This syndrome mainly affects the neurologic system, manifesting symptoms such as weekly sensation of neuropathy, which are characterized by numbness, tingling and burning sensation in the limbs. This condition is usually caused by long-term diet supplementation of vitamin B6, but it may also be caused by acute overdose (regardless of oral or external administration)."

I also ask readers to read a summary article published on 2023-2-7: Vitamin B6 Toxicity (vitamin B6) Intoxication), one of which is: "Non-pregnancy supplements are the culprits who cause pyridoxine levels to exceed the safety recommendation limit in patients. Patients usually do not realize that high doses of pyridoxine can be harmful. A demonstration case report describes a patient diagnosed by a medical institution on the weekly neuropathy, who reported that he had taken Vitamin B for ten years. The dosage of compound supplements is fifty times the recommended daily intake. According to data from the U.S. poison centers in 2017, 566 reports of treatment using pyridoxine as a detoxifier. In addition, 377 cases of pyridoxine exposure were reported, of which 8 had only minor or moderate clinical effects. No serious consequences or deaths have been reported. It is not a single chemical substance, but a family of many chemical compounds, among which pyridoxine is the most common and is also a compound in commercially available vitamin supplements]

I also ask readers to read a very special facial blog, its name is Vitamin B6 Toxicity (vitamin B6 Toxicity). (Note: The illustration in this article is copied from this face website)

Original text: Group B, is there no risk of water solubility?

Responsible editor: Gu Zihuan



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